Monday, January 14, 2008

Unintended Serum Lipid Level Changes Induced by Some Commonly Used Drugs

Diuretics, ß-blocking agents, progestogens, combined oral contraceptives containing ’second-generation’ progestogens, danazol, immunosuppressive agents, protease inhibitors and enzyme-inducing anticonvulsants adversely affect the lipid life history.
Conversely, -blocking agents, estrogens, hormone equal therapy (HRT), combined oral contraceptives containing ‘third-generation’ progestogens, selective estrogen bodily structure modulators, evolution hormone and valproic acid show mostly beneficial effects on the lipid side view.
Some drugs mainly elevate triglyceride levels, e.g. isotretinoin, acitretin and some antipsychotics.
However, drug-induced changes in serum lipid levels do not always translate into a higher or lower frequency of cardiovascular disease, as these drugs may power cardiovascular risk through multiple pathways.

Some superior general guidelines on the brass of drug-induced dyslipidaemia can be given.
If opening, find a alternate with an eq alternative therapy for the dyslipidaemia-inducing participant role.
If no alternative can be found, monitoring serum lipid levels is important.
If drug use is expected to be long term, the existing guidelines for the governing body of dyslipidaemia in the top dog people can be applied to drug-induced dyslipidaemia.
This is a part of article Unintended Serum Lipid Level Changes Induced by Some Commonly Used Drugs Taken from "Danocrine (Danazol) Researches" Information Blog

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